Manager Steve Bruce wants to sign the 29-year-old England international after season-ending injuries to Paul Dummett and Jetro Willems.
Elements of the deal are still to be resolved but Sky Sports reports that it is a £2m loan fee with no obligation to buy.
Rose has made 16 Tottenham appearances this season but only five since Jose Mourinho became manager on 20 November.
Tottenham full-back Kyle Walker-Peters has also moved on loan, to Southampton for the remainder of the season.
Tottenham defender Danny Rose has arrived at the Newcastle training ground to finalise his loan move from North London.
Rose is expected to have his medical this afternoon, according to SkySports.