A 38-year-old Nigerian, Chimezie Stanley Duru,  and a Thai woman have been arrested in Pattaya with a kilogram of crystal methamphetamine valued at 350,000 baht.

The police also nabbed two Australians in the crackdown.

46-year-old Jamie Robert Hansom and 58-year-old Steven Brett Hovi, both Australian, Chimezie Stanley Duru of Nigeria and a Thai woman, 35-year-old Jiraphon Kietsutthijit were arrested after heavily armed officers swarmed over a high metal gate of a home in the beach-side resort city of Pattaya, about 100km southeast of the capital Bangkok, about 5.30pm yesterday.

Authorities seized 1.229kg of a drug alleged to be ice; multiple guns, six mobile phones; 12 debit cards spanning seven bank accounts; 12 cash tablets and a grey Toyota Vios sedan.

Police also believed they may be connected to the Hells Angels outlaw motorcycle gang in Pattaya, according to local media.

The police described the arrests as a significant move against a global drug cartel.

The suspects were taken to a local police station to face charges.