Iconic comedian and Eddie Murphy’s elder brother Charlie Murphy has died at the age of 57, according to reports.

The stand-up comedian and actor died of leukemia in New York.

TMZ reported that his manager said he died on Wednesday morning in a New York hospital, leaving family members who had thought he was getting better while undergoing chemotherapy shocked.

He was perhaps best-known for his appearances on Chappelle’s Show on Comedy Central.

He collaborated with writing his brother’s starring films, Norbert and Vampire in Brooklyn. He voiced roles in animated TV series that include The Boondocks and Black Jesus.

Murphy’s feature films include Our Family Wedding, King’s Ransom and CB4.

He is credited with appearances to air later this year on the TV drama series Power.