Chinese researchers have recently made a breakthrough in discovering a gene responsible for deafness, providing a target for treating hearing impairment.
The study published online earlier this month in the international journal Genetics in Medicine described the gene as ABCC1, which has variants associated with hearing loss and plays a key role in maintaining cochlear function.
The cochlea is a spiral tube shaped like a snail shell. It is the auditory area of the inner ear and enables effective hearing.
Using gene screening, sequencing and other genetic analysis method, researchers from Xiangya Hospital affiliated with the Central South University in China’s Hunan Province, found the variants in gene ABCC1 could work as a pump to extrude toxic substance and metabolic waste products from the inner ear.
In experiments done on mice, they found the dysfunction of these variants could lead to hearing loss.
Hearing impairment is the most common sensory deficit, with an incidence of 1 in 500 individuals worldwide.
Aging and chronic exposure to loud noises are the main factors that contribute to hearing loss.
Since the discovery of several genes responsible for deafness in the 1990s, the role of genetic factors has received increasing attention in the scientific community.
Revealing the mechanism of how these single gene variants function can help scientists provide early warning and develop a new treatment for millions of patients who lost their hearing, said lead researcher Feng Yong.
Feng has conducted deafness gene researches for more than two decades.
His team has reported pathogenic mutations of over 20 deafness genes.
The new discovery was inspired by one of Feng’s patient.
The research team visited the patient’s hometown, conducted family surveys and at last identified the new gene, which lasted for more than three years.
“Our data also has implications for future molecular and clinical diagnosis of hearing loss,” Feng said.
Further research should be performed to determine the potential contribution of the gene to hearing loss, which will be beneficial for future treatment strategies, according to researchers.
BBNaija: Why I stopped being friends with Lucy – Dorothy
I’m bigger than celebrities who insulted me in the past – Bobrisky
BBNaija: Kemi Olunloyo speaks against celebrities paying people to vote
Messi, Suarez go emotional as Arturo Vidal leaves Barcelona
We need to play up to five games to pick form – Solskjaer
Watch Nigerian man propose to girlfriend onboard international flight
“My body no dey quick move”, Laycon tells Nengi as she touches him
We have finally caged the lions from Edo politics, says Gov. Obaseki
Why I’m scared of getting married, Actress Genevieve Nnaji reveals
Fani-Kayode berates journalist at press briefing
Joshua Iginla spits fire against CAMA in new video
Save N1,000 daily for your girlfriend’s birthday, lady advises men
Popular showbiz duo, Obi Cubana, Cubana Chief Priest part ways
Ex-convict, 50, caught raping four-year-old girl in Bauchi mosque (Photos/Video)
COVID-19: Nigeria to fine airlines which failed to ensure passengers present negative test results $3,500 per violator
Jacob in the Bible is the number one Yahoo boy- White garment prophet says
VIDEO: Jubilation in Edo as Obaseki wins Governorship election
VIDEO: School building collapses in Lagos
Vote buying: No prepaid, na see-and-buy – Edo voter (VIDEO)
VIDEO: Uber, Bolt drivers protest in Abuja
VIDEO: INEC is failing us, card readers not working – Oshiomhole
VIDEO: Kwara First Lady, Emir reconciled us, mended our broken marriage – Blue-eyed woman, husband say
Will your teeth NOT regrow if a lizard should see it after it falls off?
Busted: Lagos sim card syndicate that steals money through transfers (VIDEO)
- Entertainment23 hours ago
Marriage isn’t an achievement, Yvonne Nelson slams critic
- General19 hours ago
Men between the ages of 19 and 27 are liabilities, don’t date them – Dr Toolz
- Crime15 hours ago
Gov Wike urges security agencies to bring oil thieves to justice
- Sports18 hours ago
Nigerian-born athletes making waves in combat sports
- Sports15 hours ago
Rohr calls 25 for Cote d’Ivoire, Tunisia friendlies
- Metro22 hours ago
Missing girl’s body found in neighbour’s wardrobe
- Entertainment17 hours ago
Kobe Bryant’s wife kicks mother out of his house
- Entertainment18 hours ago
PHOTOS: DJ Cuppy shows off billionaire father’s Rolls Royce