The two African football big wigs will lock horns in Alexandria on Saturday.
The Super Eagles qualified for the knockout phase after finishing as runners-up in Group B following their shocking 2-0 defeat to Madagascar.
The Indomitable Lions were held to a 0-0 draw by Benin, who sealed their place in the knockout stages for the first time.
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Benin held on for a point that means they will progress as one of the four best third-place teams and are likely to face hosts Egypt or Morocco, with South Africa now awaiting the result of Tuesday night’s final fixtures in Group E to see if they have qualified.
Meanwhile, Ghana’s 2-0 victory over Guinea-Bissau ensured that the Black Stars topped Group F and they will now face the runner-up from Group E.
